miRarchitect is a machine learning-based tool for rational design of artificial miRNAs. The design process involves analyzing the target sequence (input), designing and studying the structure and thermodynamics of siRNA, selecting the best native pri-miRNA scaffold, and developing amiRNA.

Data upload

Target specification

Design parametrization

Design and results

Select one input option to proceed:

1) Enter a gene/transcript identifier (accession number or name)

2) Paste a nucleotide sequence (full target sequence <5000nt)

and/or insert 21-24nt target sequence(s) (separated by commas or semicolons)

3) Upload data from...

local file (.fasta)

ready-made example

miRarchitect

Overview

Help

Cite us

Select one input option to proceed:

1) Enter a gene/transcript identifier (accession number or name)

2) Paste a nucleotide sequence (full target sequence <5000nt)

and/or insert 21-24nt target sequence(s) (separated by commas or semicolons)

3) Upload data from...

4) Provide a task ID (to retrieve previous results)